Introduction



The principles and application of common methods used for detection and analysis of macromolecular structure, function, and interaction will be discussed. This course covers biochemical methods of separation and detection of macromolecules as well as molecular analysis. Recombinant DNA methods including cloning and gene expression, DNA sequencing, PCR, mutagenesis and nucleic acid and protein labeling will covered in this course including introductory biostatistics.

Course Objectives

The goals of the course are: to develop an understanding of:

• The basic methods applied to the study of proteins and nucleic acids.
  
• The instrumentation used for these methods.
• The ways that these methods and techniques are applied to study of macromolecules, i.e., have some idea what methods can/should be used to study a particular problem.

Duration

The course runs for 20 hours over a 6 week session